Detalhe da pesquisa
1.
A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge.
Am J Respir Crit Care Med
; 208(8): 868-878, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37556679
2.
Human Infection Challenge with Serotype 3 Pneumococcus.
Am J Respir Crit Care Med
; 206(11): 1379-1392, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802840
3.
Thirteen-Valent Pneumococcal Conjugate Vaccine-Induced Immunoglobulin G (IgG) Responses in Serum Associated With Serotype-Specific IgG in the Lung.
J Infect Dis
; 225(9): 1626-1631, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34159375
4.
Experimental Human Pneumococcal Colonization in Older Adults Is Feasible and Safe, Not Immunogenic.
Am J Respir Crit Care Med
; 203(5): 604-613, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32941735
5.
Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.
Am J Respir Crit Care Med
; 201(3): 335-347, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31626559
6.
Saliva Alternative to Upper Respiratory Swabs for SARS-CoV-2 Diagnosis.
Emerg Infect Dis
; 26(11): 2770-2771, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32917294
7.
Pneumococcal Colonization in Healthy Adult Research Participants in the Conjugate Vaccine Era, United Kingdom, 2010-2017.
J Infect Dis
; 219(12): 1989-1993, 2019 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30690468
8.
Serotype 3 Experimental Human Pneumococcal Challenge (EHPC) study protocol: dose ranging and reproducibility in a healthy volunteer population (challenge 3).
BMJ Open
; 14(1): e075948, 2024 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199622
9.
Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study.
Eur Respir J
; 52(4)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30305331
10.
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination.
Nat Commun
; 14(1): 6815, 2023 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37884506
11.
Comprehensive review of safety in Experimental Human Pneumococcal Challenge.
PLoS One
; 18(5): e0284399, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37141259
12.
Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccharide vaccine on pneumococcal colonisation using the experimental human pneumococcal challenge model in healthy adults (PREVENTING PNEUMO 2).
BMJ Open
; 12(7): e062109, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35798520
13.
Twelve lateral flow immunoassays (LFAs) to detect SARS-CoV-2 antibodies.
J Infect
; 84(3): 355-360, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34906597
14.
Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2.
J Clin Invest
; 132(7)2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35139037
15.
Symptoms associated with influenza vaccination and experimental human pneumococcal colonisation of the nasopharynx.
Vaccine
; 38(10): 2298-2306, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32035708
16.
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization.
J Clin Invest
; 129(10): 4523-4538, 2019 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31361601
17.
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization.
J Clin Invest
; 132(11)2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35642639